Al-Kāfi - Volume 6 > Wine is Prohibited because of its Effects; whatever has an Effect as the Effect of Wine, it is Wine
Hadith #3

عِدَّةٌ مِنْ أَصْحَابِنَا عَنْ سَهْلِ بْنِ زِيَادٍ وَ عَلِيُّ بْنُ إِبْرَاهِيمَ عَنْ أَبِيهِ جَمِيعاً عَنْ عَمْرِو بْنِ عُثْمَانَ عَنْ مُحَمَّدِ بْنِ عَبْدِ اللَّهِ عَنْ بَعْضِ أَصْحَابِنَا قَالَ قُلْتُ لِأَبِي عَبْدِ اللَّهِ ( عليه السلام ) لِمَ حَرَّمَ اللَّهُ الْخَمْرَ فَقَالَ حَرَّمَهَا لِفِعْلِهَا وَ مَا تُؤَثِّرُ مِنْ فَسَادِهَا .

3. A number of our people have narrated from Sahl ibn Ziyad and Ali ibn Ibrahim has narrated from his father all from ‘Amr ibn ‘Uthman from Muhammad ibn ‘Abd Allah from certain persons of our people who has said the following: “I once asked abu ‘Abd Allah, ‘Alayhi al-Salam, ‘Why has Allah prohibited wine?’ He (the Imam) said, ‘He has prohibited it because of its effects and the destructive effects that it leaves behind.’”